Usually, I do not observe burn-in changes. Many listen and observe changes every 10th hour. I let my players run in for 100 hours with a new IEM / Headphone that needs to be burned in. I do not listen in between and I can never trust my audio memory from 4 days ago. I have a feeling that these Chinese players (QA350 and HM-601) need to be run in anyways to prove that they are stable. If they can do 50 hours without issues, you can be sure that it's not going to go out on you within a 2 hour listening session within the next week or two. As for changes, may be there are, may be not. I liked FX700 initially out of HM-601's HO somewhat, now I am not so fond of it. May be it got a bit more louder?
As for synergy, broadly my observations are important than my comments. Unless you are going to listen to death metal all the time, those synergies have little meaning for you. Secondly, I have tried them out of various sources and I have a hint of what changes HM-601 could be doing to their frequency response. You may not, if you are going to use them all the time with 601. Secondly, what I place emphasis on and what you place emphasis on would be different. So, my overall thoughts are more important than what I think has better synergy.
With a headphone amp, you would not have the effect of high Output impedance. So, it could be better. Are you getting Arrow 3G from Head-fi? Why did you choose Arrow? Have you considered other amps?
@matbhuvi,
No! Even if I try Hi-Res files (which I do not have), HM-601 would down sample them to 16/44. A head-fier once mentioned to me that the difference between 24/96 and 16/44 has more to do with the recording and hence even if 601 down samples, they sound better.
I've not tried DT880 or any others so far. It was already late last night. May be tomorrow