These low power amps are created using chips like tripath etc. Technically speaking, they sound great if the speakers connected are very sensitive. I know someone who runs a high end audionote speaker with the amptastic mini. Works fine. He has an audionote amp too. However, the speaker is very sensitive and created with low power tube amps in mind.
With normal speakers (even the ones that are around 90db), stay with traditional amplifiers. The tiny fellas will not have any power reserves. Bass gets weak and high gets harsh as a consequence. And music will sound like it is all happening in slow motion.